University of Minnesota
School of Physics & Astronomy

Biophysics Seminar

Tuesday, November 9th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Theoden Netoff, University of Minnesota, Biomedical Engineering
Subject: Dynamical approaches to understanding the mechanisms of seizure genesis and treatment

Epilepsy is a complex disease where causes and treatments occur at the scale of ion channels but the disease represents as a behavior at the cortical scale. There are many scales to bridge from the molecular to behavior to understand this disease better. Our research uses dynamical systems analysis to understand how antiepileptic drugs affect neuronal dynamics and in turn how those changes affect network synchrony. By bridging these scales we can understand how and why antiepileptic drugs prevent seizures and changes in synchrony occur during seizures.

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