University of Minnesota
School of Physics & Astronomy

Nuclear Physics Seminar

Friday, February 26th 2016
11:15 am:
Speaker: Yao Leon Meng, University of Minnesota
Subject: Feasibility of Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT)

Boron Neutron Capture Therapy is a promising option for the treatment of glioblastoma and other recurrent brain/neck/breast cancers. Although successful clinical trials have been made using nuclear reactors, BNCT application need neutron sources which are suitable to be installed in hospitals. Particle accelerators are appropriate for this purpose. I will overview the possible nuclear reactions as a neutron source 7Li(p,n)7Be, Be9(p,n)B9, D+T, etc and the corresponding target design,neutron moderation challenge. I will introduce the application of nuclear data library and Geant4 Monte Carlo code in BNCT study. The progress of new pre-clinical neutron absorbing agents based on nano medicine and other techniques will also be reviewed briefly.

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