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BESIII now holds the world's largest e+e- annihilation samples taken at Ecm = 3.773 and 4.178 GeV which produce copious charmed mesons, D0, D+, and Ds+. In this talk, I would like to report our on-going studies on D+ -> l nu and
Ds -> l nu (l = mu and tau). These allow us to determine the elements of the CKM matrix within the standard model, to test the unitarity of the second rows of the CKM matrix, probe lepton universality, as well as to calibrate the LQCD calculations of the decay constants, fD(s)+.
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