Biophysics Seminar

semester, 2010


Monday, February 8th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Jonathan Sachs, University of Minnesota
Subject: To be announced

Tuesday, February 9th 2010
2:30 pm:
Biophysics Seminar in 166 Physics
There will be no seminar this week.

Tuesday, February 16th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
There will be no seminar this week.

Tuesday, February 23rd 2010
2:30 pm:
Biophysics Seminar in 170 Physics
Speaker: Aaron Wynveen, University of Minnesota
Subject: Mutual sequence homology recognition of intact DNA double helices

Tuesday, March 2nd 2010
2:30 pm:
Biophysics Seminar in 170 Physics
Speaker: Steve Gardeeen, University of Minnesota
Subject: Observing the "mismatch" magnetic field response in the human brain caused by auditory discrimination of changes in heavily damped frequency components of a complex sound.

Tuesday, March 9th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
To be announced.

Tuesday, March 16th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
There will be seminar this week.

Tuesday, March 23rd 2010
2:30 pm:
Biophysics Seminar in 170 Physics
There will be no seminar this week.

Tuesday, March 30th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
Speaker: Marc Riedel, Electrical and Computer Engineering, University of Minnesota
Subject: Computing with Things Small, Wet, and Random: Design Automation for Nanoscale Technologies and Biological Processes

This talk will discuss techniques for synthesizing circuits and biological systems that are characterized by uncertainty in the way that they are wired or that they execute. We adopt a novel view of computation: instead of transforming definite inputs into definite outputs, circuits and biological systems transform probability values into probability values. The computation is random at the level of bits or protein-protein reactions; nonetheless, in the aggregate, it becomes exact and robust, since the accuracy depends only on the statistical distributions. The talk will present novel circuit constructs that are analog in character but based on digital components. Also, it will present biological constructs that are digital in character in the sense that they deliver robust outcomes. We propose a bio-design automation flow in which synthesis first is performed at a conceptual level, in terms of abstract biochemical reactions -- a task analogous to technology independent logic synthesis in circuit design. Then the results are mapped onto specific biochemical reactions, selected from libraries -- a task analogous to technology mapping in circuit design. Our method targets DNA strand displacement, developed by Erik Winfree's group at Caltech, as the experimental chassis. Biography: Marc Riedel has been an Assistant Professor of Electrical and Computer Engineering at the University of Minnesota since 2006. He is also a member of the Graduate Faculty in Biomedical Informatics and Computational Biology. He has held positions at Marconi Canada, CAE Electronics, Toshiba, and Fujitsu Research Labs. He received his Ph.D. and his M.Sc. in Electrical Engineering at Caltech and his B.Eng. in Electrical Engineering with a Minor in Mathematics at McGill University. His Ph.D. dissertation titled "Cyclic Combinational Circuits" received the Charles H. Wilts Prize for the best doctoral research in Electrical Engineering at Caltech. His paper "The Synthesis of Cyclic Combinational Circuits" received the Best Paper Award at the Design Automation Conference. He is a recipient of the NSF CAREER Award.


Tuesday, April 6th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
To be announced.

Tuesday, April 13th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
Speaker: Professor Susanta Hui, Department of Therapeutic Radiology, University of Minnesota
Subject: : Longitudinal monitoring of radiation effect on bone in a murine model

Due to success in anti-cancer therapies, cancer survivor’s bone health is becoming important for comprehensive cancer treatment management. Detrimental effects of cancer therapies, including radiation, hormonal therapy, chemotherapy, and glucocorticoid on bone health has become a major concern due to an increased risk for bone fracture and other morbidities, and decreases in survival rates. We will present a recently developed, clinically relevant murine model to address various biophysical effects of radiation on bone health and response to antiresorptive therapy.


Tuesday, April 20th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
Speaker: Yan Chen, University of Minnesota
Subject: Nuclear receptors, ligands and coactivators: A study of their interactions using Fluorescence Fluctuation Spectroscopy

Tuesday, April 27th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
There will be no seminar this week.

Tuesday, May 4th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
To be announced.

Tuesday, May 11th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
There will be no seminar this week.

Tuesday, September 7th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
To be announced.

Tuesday, September 14th 2010
2:30 pm:
Biophysics Seminar in 170 Physics
To be announced.

Tuesday, September 21st 2010
2:30 pm:
Biophysics Seminar in 170 Physics
Speaker: Pamela Sooriyan, University of Minnesota
Subject: Dose enhancement in bone due to giant dipole resonance of Ca-40 with photons of 14-20 MeV.
To be announced.

At photon energy of 14-20 MeV, Compton scattering and absorption by pair production are the predominant photon interaction processes. Bone, with a higher atomic number and higher electron density than that of tissue, will absorb more dose than tissue due to both these interaction processes. In addition, maximizing the element selective giant dipole resonance would cause a further significant increase in dose enhancement in the vicinity of bone. This would increase the possibility of delivering a lethal dose to the tumor in or around the bone while keeping dose to normal surrounding tissue as low as possible.


Tuesday, September 28th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Pamela Sooriyan, University of Minnesota
Subject: TBA
Note change of room for this seminar, this semester.

Tuesday, October 5th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
There will be no seminar this week.

Tuesday, October 12th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Roy Bar-Ziv, Weizmann Institute
Subject: Reconstructing synthetic cellular compartments on a surface

Tuesday, October 19th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
There will be no seminar this week.

Tuesday, October 26th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Greg Fairchild, Biophysical Science and Medical Physics Department
Subject: The Influence of Therapeutic Radiation Doses on the Pattern of Remodeling in Healthy and Estrogen-deficient Bone.

Tuesday, November 2nd 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Time to be announced.

Tuesday, November 9th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Theoden Netoff, University of Minnesota, Biomedical Engineering
Subject: Dynamical approaches to understanding the mechanisms of seizure genesis and treatment

Epilepsy is a complex disease where causes and treatments occur at the scale of ion channels but the disease represents as a behavior at the cortical scale. There are many scales to bridge from the molecular to behavior to understand this disease better. Our research uses dynamical systems analysis to understand how antiepileptic drugs affect neuronal dynamics and in turn how those changes affect network synchrony. By bridging these scales we can understand how and why antiepileptic drugs prevent seizures and changes in synchrony occur during seizures.


Tuesday, November 16th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
There will be no seminar this week.

Tuesday, November 23rd 2010
2:30 pm:
Biophysics Seminar in 210 Physics
There will be no seminar this week.

Tuesday, November 30th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Luke Arentsen, University of Minnesota, Biomedical Engineering.
Subject: Cancer treatment effects on cancellous bone remodeling using Quantitative Computed Tomography.

Tuesday, December 7th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
There will be no seminar this week.

Tuesday, December 14th 2010
2:30 pm:
Biophysics Seminar in 210 Physics
Speaker: Victor Barocas, Biomedical Engineering.
Subject: Mechanical models of fibrous tissue

Tuesday, December 21st 2010
2:30 pm:
Biophysics Seminar in 210 Physics
No seminar. Finals week.

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